In cross-presentation, antigens are brought into the APC by mechanisms usually resulting in presentation with MHC II (i.e., by phagocytosis), but the antigen is offered on an MHC I molecule for CD8 T cells. The precise mechanisms by which cross-presentation occur are usually not yet well understood, but it seems that cross-presentation is primarily a perform of dendritic cells and not macrophages or B cells. Compare and contrast antigen processing and presentation related to MHC I and MHC II molecules. What is cross-presentation, and when is it more likely to happen? Outdoors, you possibly can place the construction on concrete, gravel, sand, rubber mulch, or poured rubber quite than directly on grass to reduce water harm and make sure the construction sits evenly. The producer of your playhouse will seemingly have recommendations for the easiest way to install it. Indoors, consider inserting it on a rug or foam mat to add cushioning. Samson McDougall is a journalist, copywriter, editor, and biology graduate. If we are in a position to connect with that wounded side of self with compassion and curiosity, build belief and relationship with them, it is possible to raised intuit and tend to their wants. With an elevated sense of security, the protection system could now not be needed in the identical manner. Personification may be useful when identifying the protecting shell and connecting with the wounded core.

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